SUCRALOSE

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 96K6UQ3ZD4

Structure
InChI Key BAQAVOSOZGMPRM-KBFHZYTNSA-N
Smile OC[C@@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H](O)[C@H]1Cl
InChI
InChI=1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5+,6+,7-,8+,9+,10+,11-,12+/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C12H19Cl3O8
Molecular Weight 397.64
AlogP -1.66
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 5.0
Number of Rotational Bond 5.0
Polar Surface Area 128.84
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 23.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Lyase
- - - 2200 -
Enzyme Transferase
- - - - 15.67
Epigenetic regulator Eraser Histone deacetylase HDAC class IIb
- - - - -15.08-11.28
Membrane receptor Taste family G protein-coupled receptor Taste receptor (taste family GPCR)
16690000-16690000 - - - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Diabetes Mellitus, Type 2 3 D003924 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL2107529
FDA SRS 96K6UQ3ZD4
PubChem 70683051
ZINC ZINC000004214346
CONTENTS