| Synonyms: | |
| Status: | Phase 1 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C13H17N5O5S |
| Molecular Weight | 355.38 |
| AlogP | -1.1 |
| Hydrogen Bond Acceptor | 7.0 |
| Hydrogen Bond Donor | 5.0 |
| Number of Rotational Bond | 6.0 |
| Polar Surface Area | 171.29 |
| Molecular species | None |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 24.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| AGONIST | Metabotropic glutamate receptor 2 agonist |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Transferase
|
- | - | - | - | 7.06 | |
|
Epigenetic regulator
Eraser
Histone deacetylase
HDAC class IIb
|
- | - | - | - | -26.69--4.86 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Bipolar Disorder | 1 | D001714 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL3544939 |
CONTENTS