DANICAMTIV

Search structure
Synonyms:
Status: Phase 1
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 7B2CS922HI

Structure
InChI Key NREKKBAMVWQRES-MRXNPFEDSA-N
Smile Cn1cc(S(=O)(=O)[C@@](C)(F)C2CCN(C(=O)Nc3ccon3)CC2)c(C(F)F)n1
InChI
InChI=1S/C16H20F3N5O4S/c1-16(19,29(26,27)11-9-23(2)21-13(11)14(17)18)10-3-6-24(7-4-10)15(25)20-12-5-8-28-22-12/h5,8-10,14H,3-4,6-7H2,1-2H3,(H,20,22,25)/t16-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C16H20F3N5O4S
Molecular Weight 435.43
AlogP 2.75
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 5.0
Polar Surface Area 110.33
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 29.0

Pharmacology

Action Mechanism of Action Reference
ACTIVATOR Cardiac myosin activator PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Cardiomyopathy, Dilated 2 D002311 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL4594304
FDA SRS 7B2CS922HI
PubChem 122424426
SureChEMBL SCHEMBL17942536
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