Synonyms: | |
Status: | Phase 2 |
Entry Type: | Small molecule |
Molecule Category: | UNKNOWN |
UNII: | S6G4R7DI1C |
InChI Key | YPFZMBHKIVDSNR-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C23H33N7O5S |
Molecular Weight | 519.63 |
AlogP | 1.12 |
Hydrogen Bond Acceptor | 10.0 |
Hydrogen Bond Donor | 1.0 |
Number of Rotational Bond | 10.0 |
Polar Surface Area | 135.54 |
Molecular species | NEUTRAL |
Aromatic Rings | 3.0 |
Heavy Atoms | 36.0 |
Action | Mechanism of Action | Reference |
---|---|---|
INHIBITOR | Phosphodiesterase 5A inhibitor | PubMed |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Enzyme
Phosphodiesterase
Phosphodiesterase 5
Phosphodiesterase 5A
|
- | 1 | - | - | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Prostatic Hyperplasia | 2 | D011470 | ClinicalTrials |
Urinary Bladder, Overactive | 2 | D053201 | ClinicalTrials |
Erectile Dysfunction | 2 | D007172 | ClinicalTrials |
Pulmonary Disease, Chronic Obstructive | 1 | D029424 | ClinicalTrials |
Resources | Reference |
---|---|
ChEMBL | CHEMBL1928262 |
DrugBank | DB11902 |
FDA SRS | S6G4R7DI1C |
Guide to Pharmacology | 6558 |
PubChem | 135536943 |
SureChEMBL | SCHEMBL19518055 |
ZINC | ZINC000034016204 |