Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: JSK7TUA223

Structure

InChI Key NALAUGMPMIVAOW-UHFFFAOYSA-N
Smile O=C(O)CNC(=O)c1c(O)cc(CCc2ccccc2)n2ncnc12
InChI
InChI=1S/C17H16N4O4/c22-13-8-12(7-6-11-4-2-1-3-5-11)21-16(19-10-20-21)15(13)17(25)18-9-14(23)24/h1-5,8,10,22H,6-7,9H2,(H,18,25)(H,23,24)

Physicochemical Descriptors

Property Name Value
Molecular Formula C17H16N4O4
Molecular Weight 340.34
AlogP 1.03
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 6.0
Polar Surface Area 116.82
Molecular species ACID
Aromatic Rings 3.0
Heavy Atoms 25.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Egl nine homolog 1 inhibitor PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Renal Insufficiency, Chronic 3 D051436 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL4297619
DrugBank DB14985
FDA SRS JSK7TUA223
PubChem 50899324
SureChEMBL SCHEMBL1481440