MK-0773

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 5730VNW22X

Structure
InChI Key GBEUKTWTUSPHEE-PAWGCEJPSA-N
Smile CN1C(=O)C(F)=C[C@]2(C)C3CC[C@@]4(C)C(CC[C@@H]4C(=O)NCc4nc5ncccc5[nH]4)C3CCC12
InChI
InChI=1S/C27H34FN5O2/c1-26-11-10-17-15(6-9-21-27(17,2)13-19(28)25(35)33(21)3)16(26)7-8-18(26)24(34)30-14-22-31-20-5-4-12-29-23(20)32-22/h4-5,12-13,15-18,21H,6-11,14H2,1-3H3,(H,30,34)(H,29,31,32)/t15?,16?,17?,18-,21?,26+,27-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C27H34FN5O2
Molecular Weight 479.6
AlogP 4.13
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 3.0
Polar Surface Area 90.98
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 35.0

Pharmacology

Action Mechanism of Action Reference
MODULATOR Androgen Receptor modulator PubMed PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Sarcopenia 2 D055948 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL3545333
FDA SRS 5730VNW22X
PubChem 11950726
SureChEMBL SCHEMBL13604131
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