| Synonyms: | |
| Status: | Phase 1 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C39H43ClN4O9S2 |
| Molecular Weight | 811.38 |
| AlogP | 6.11 |
| Hydrogen Bond Acceptor | 13.0 |
| Hydrogen Bond Donor | 6.0 |
| Number of Rotational Bond | 15.0 |
| Polar Surface Area | 182.68 |
| Molecular species | None |
| Aromatic Rings | 5.0 |
| Heavy Atoms | 55.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| AGONIST | Beta-2 adrenergic receptor agonist |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Membrane receptor
Family A G protein-coupled receptor
Small molecule receptor (family A GPCR)
Monoamine receptor
Acetylcholine receptor
|
- | 1.585-1.6 | - | - | - | |
|
Membrane receptor
Family A G protein-coupled receptor
Small molecule receptor (family A GPCR)
Monoamine receptor
Adrenergic receptor
|
0.2512 | 1.6 | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Pulmonary Disease, Chronic Obstructive | 1 | D029424 | ClinicalTrials |
| Asthma | 1 | D001249 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL3545272 |
CONTENTS