Synonyms: | |
Status: | Phase 2 |
Entry Type: | Small molecule |
Molecule Category: | UNKNOWN |
UNII: | 6PJC3KPK6S |
InChI Key | YZOQZEXYFLXNKA-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C17H23N5O2S |
Molecular Weight | 361.47 |
AlogP | 2.06 |
Hydrogen Bond Acceptor | 6.0 |
Hydrogen Bond Donor | 2.0 |
Number of Rotational Bond | 7.0 |
Polar Surface Area | 102.9 |
Molecular species | NEUTRAL |
Aromatic Rings | 3.0 |
Heavy Atoms | 25.0 |
Action | Mechanism of Action | Reference |
---|---|---|
AGONIST | Toll-like receptor 7 agonist | PubMed |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Membrane receptor
Toll-like and Il-1 receptors
|
2657 | - | - | - | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Melanoma | 2 | D008545 | ClinicalTrials |
Melanoma | 2 | D008545 | ClinicalTrials |
Neoplasms | 1 | D009369 | ClinicalTrials |
Resources | Reference |
---|---|
ChEMBL | CHEMBL549344 |
DrugBank | DB12476 |
EPA CompTox | DTXSID20201416 |
FDA SRS | 6PJC3KPK6S |
Guide to Pharmacology | 9025 |
PubChem | 10309114 |
SureChEMBL | SCHEMBL483385 |