LENIOLISIB PHOSPHATE

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 3700M1H39Q

Structure
InChI Key XXEDEGOAYSGNPS-ZOWNYOTGSA-N
Smile CCC(=O)N1CC[C@H](Nc2ncnc3c2CN(c2cnc(OC)c(C(F)(F)F)c2)CC3)C1.O=P(O)(O)O
InChI
InChI=1S/C21H25F3N6O2.H3O4P/c1-3-18(31)30-6-4-13(10-30)28-19-15-11-29(7-5-17(15)26-12-27-19)14-8-16(21(22,23)24)20(32-2)25-9-14;1-5(2,3)4/h8-9,12-13H,3-7,10-11H2,1-2H3,(H,26,27,28);(H3,1,2,3,4)/t13-;/m0./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C21H28F3N6O6P
Molecular Weight 548.46
AlogP 2.88
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 5.0
Polar Surface Area 83.48
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 32.0

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Sjogren's Syndrome 2 D012859 ClinicalTrials
Common Variable Immunodeficiency 2 D017074 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL3989909
FDA SRS 3700M1H39Q
PubChem 90214495
SureChEMBL SCHEMBL15789519
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