| Synonyms: | |
| Status: | Approved (2011) |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | T2I5UM75DN |
Structure
| InChI Key | IOVCWXUNBOPUCH-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | HNO2 |
| Molecular Weight | 47.01 |
| AlogP | 0.14 |
| Hydrogen Bond Acceptor | 2.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 0.0 |
| Polar Surface Area | 49.66 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 0.0 |
| Heavy Atoms | 3.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Lyase
|
- | - | - | 63000000-63000000 | - | |
|
Enzyme
|
- | - | - | 63000000-63000000 | - | |
|
Epigenetic regulator
Eraser
Histone deacetylase
HDAC class IIb
|
- | - | - | - | 10.98-40.93 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Heart Arrest | 1 | D006323 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 25567 |
| ChEMBL | CHEMBL1161681 |
| DrugBank | DB09112 |
| EPA CompTox | DTXSID7064813 |
| FDA SRS | T2I5UM75DN |
| Human Metabolome Database | HMDB0002786 |
| KEGG | C00088 |
| PDB | 2NO |
| PubChem | 24529 |
| SureChEMBL | SCHEMBL1057 |
CONTENTS