AFACIFENACIN

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: XQU62QZ74P

Structure
InChI Key IJUMFEAYOMCXAQ-UHFFFAOYSA-N
Smile O=C1Nc2ccccc2C(c2ccccc2)N1C1CCN(Cc2cccc(OC(F)(F)F)c2)CC1
InChI
InChI=1S/C27H26F3N3O2/c28-27(29,30)35-22-10-6-7-19(17-22)18-32-15-13-21(14-16-32)33-25(20-8-2-1-3-9-20)23-11-4-5-12-24(23)31-26(33)34/h1-12,17,21,25H,13-16,18H2,(H,31,34)

Physicochemical Descriptors

Property Name Value
Molecular Formula C27H26F3N3O2
Molecular Weight 481.52
AlogP 6.19
Hydrogen Bond Acceptor 3.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 5.0
Polar Surface Area 44.81
Molecular species NEUTRAL
Aromatic Rings 3.0
Heavy Atoms 35.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Muscarinic acetylcholine receptor antagonist Other Other

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Urinary Bladder, Overactive 2 D053201 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL3545165
FDA SRS XQU62QZ74P
PubChem 42647276
SureChEMBL SCHEMBL1192029
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