YM-543

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: KA83KI0EO9

Structure
InChI Key AGJJCLBOHJQGFA-ZQGJOIPISA-N
Smile OC[C@H]1O[C@@H](c2cc(Cc3cc4cccccc-4c3)ccc2O)[C@H](O)[C@@H](O)[C@@H]1O
InChI
InChI=1S/C23H24O6/c24-12-19-20(26)21(27)22(28)23(29-19)17-11-13(6-7-18(17)25)8-14-9-15-4-2-1-3-5-16(15)10-14/h1-7,9-11,19-28H,8,12H2/t19-,20-,21+,22-,23+/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C28H37NO7
Molecular Weight 499.6
AlogP 1.6
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 5.0
Number of Rotational Bond 4.0
Polar Surface Area 110.38
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 29.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Sodium/glucose cotransporter 2 inhibitor

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Diabetes Mellitus, Type 2 2 D003924 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL2397450
FDA SRS KA83KI0EO9
PubChem 11560307
SureChEMBL SCHEMBL980608
ZINC ZINC000003939471
ChEMBL CHEMBL4297452
FDA SRS KA83KI0EO9
PubChem 11560307
SureChEMBL SCHEMBL980608
CONTENTS