Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: FX5AUU7Z8T

Structure

InChI Key BDABGOLMYNHHTR-UHFFFAOYSA-N
Smile O=c1c2c(c1=O)N(CCP(=O)(O)O)CCCN2
InChI
InChI=1S/C9H13N2O5P/c12-8-6-7(9(8)13)11(3-1-2-10-6)4-5-17(14,15)16/h10H,1-5H2,(H2,14,15,16)

Physicochemical Descriptors

Property Name Value
Molecular Formula C9H13N2O5P
Molecular Weight 260.19
AlogP -0.92
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 3.0
Polar Surface Area 106.94
Molecular species ACID
Aromatic Rings 1.0
Heavy Atoms 17.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Glutamate [NMDA] receptor antagonist PubMed PubMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Ion channel Ligand-gated ion channel Ionotropic glutamate receptor NMDA receptor
- 8-30 - - -

Cross References

Resources Reference
ChEMBL CHEMBL452461
DrugBank DB12365
EPA CompTox DTXSID70162846
FDA SRS FX5AUU7Z8T
PubChem 6918236
SureChEMBL SCHEMBL371400
ZINC ZINC000026496985