| Synonyms: | |
| Status: | Phase 2 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 4S145C552U |
Structure
| InChI Key | YCNIQYLWIPCLNY-QHCPKHFHSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C23H20N2O5 |
| Molecular Weight | 404.42 |
| AlogP | 3.04 |
| Hydrogen Bond Acceptor | 7.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 3.0 |
| Polar Surface Area | 87.49 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 30.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | DNA topoisomerase I inhibitor | ClinicalTrials PubMed |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Small Cell Lung Carcinoma | 2 | D055752 | ClinicalTrials |
| Lymphoma | 1 | D008223 | ClinicalTrials |
| Neoplasms | 1 | D009369 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL124162 |
| EPA CompTox | DTXSID30173074 |
| FDA SRS | 4S145C552U |
| SureChEMBL | SCHEMBL1618775 |
| ZINC | ZINC000003828515 |
CONTENTS