BAVISANT

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 9827P7LFVH

Structure
InChI Key BGBVSGSIXIIREO-UHFFFAOYSA-N
Smile O=C(c1ccc(CN2CCOCC2)cc1)N1CCN(C2CC2)CC1
InChI
InChI=1S/C19H27N3O2/c23-19(22-9-7-21(8-10-22)18-5-6-18)17-3-1-16(2-4-17)15-20-11-13-24-14-12-20/h1-4,18H,5-15H2

Physicochemical Descriptors

Property Name Value
Molecular Formula C19H27N3O2
Molecular Weight 329.44
AlogP 1.44
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 0.0
Number of Rotational Bond 4.0
Polar Surface Area 36.02
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 24.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Histamine H3 receptor antagonist PubMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Histamine receptor
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Indications

Mesh Heading Maximum Phase Mesh ID Reference
Attention Deficit Disorder with Hyperactivity 2 D001289 ClinicalTrials
Alcoholism 2 D000437 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL2103862
DrugBank DB12299
FDA SRS 9827P7LFVH
PubChem 16061509
SureChEMBL SCHEMBL522603
ZINC ZINC000034962220
CONTENTS