| Status: | Phase 2 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 3J396119JY |
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C23H22FN5O4S |
| Molecular Weight | 483.53 |
| AlogP | 3.64 |
| Hydrogen Bond Acceptor | 8.0 |
| Hydrogen Bond Donor | 3.0 |
| Number of Rotational Bond | 9.0 |
| Polar Surface Area | 122.31 |
| Molecular species | None |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 34.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | Tyrosine-protein kinase JAK3 inhibitor |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Dry Eye Syndromes | 2 | D015352 | ClinicalTrials |
| Bronchiolitis Obliterans Syndrome | 2 | D000092122 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL3545382 |
| FDA SRS | 3J396119JY |
| PubChem | 23648971 |
CONTENTS