| Synonyms: | |
| Status: | Phase 2 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 2GTU230HA1 |
Structure
| InChI Key | MTJHLONVHHPNSI-IBGZPJMESA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C24H30N6O2 |
| Molecular Weight | 434.54 |
| AlogP | 4.95 |
| Hydrogen Bond Acceptor | 6.0 |
| Hydrogen Bond Donor | 3.0 |
| Number of Rotational Bond | 9.0 |
| Polar Surface Area | 101.06 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 32.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | Tubulin inhibitor | PubMed |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Multiple Myeloma | 2 | D009101 | ClinicalTrials |
| Glioblastoma | 1 | D005909 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 95005 |
| ChEMBL | CHEMBL552212 |
| EPA CompTox | DTXSID10238675 |
| FDA SRS | 2GTU230HA1 |
| PDB | LXL |
| PubChem | 11351021 |
| SureChEMBL | SCHEMBL1122311 |
| ZINC | ZINC000043024000 |
CONTENTS