Synonyms: | |
Status: | Phase 2 |
Entry Type: | Small molecule |
Molecule Category: | UNKNOWN |
UNII: | T61871RKRI |
InChI Key | JRNJNYBQQYBCLE-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C18H21F2N5O4S |
Molecular Weight | 441.46 |
AlogP | 1.41 |
Hydrogen Bond Acceptor | 8.0 |
Hydrogen Bond Donor | 2.0 |
Number of Rotational Bond | 6.0 |
Polar Surface Area | 127.51 |
Molecular species | NEUTRAL |
Aromatic Rings | 2.0 |
Heavy Atoms | 30.0 |
Action | Mechanism of Action | Reference |
---|---|---|
INHIBITOR | Cyclin-dependent kinase 1 inhibitor |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Neoplasms | 1 | D009369 | ClinicalTrials |
Resources | Reference |
---|---|
ChEMBL | CHEMBL384304 |
DrugBank | DB08094 |
EPA CompTox | DTXSID30225143 |
FDA SRS | T61871RKRI |
Guide to Pharmacology | 5707 |
PDB | LIA |
SureChEMBL | SCHEMBL2397067 |
ZINC | ZINC000013983251 |