DRINABANT

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 61S98RLL5I

Structure
InChI Key IQQBRKLVEALROM-UHFFFAOYSA-N
Smile CS(=O)(=O)N(c1cc(F)cc(F)c1)C1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1
InChI
InChI=1S/C23H20Cl2F2N2O2S/c1-32(30,31)29(21-11-19(26)10-20(27)12-21)22-13-28(14-22)23(15-2-6-17(24)7-3-15)16-4-8-18(25)9-5-16/h2-12,22-23H,13-14H2,1H3

Physicochemical Descriptors

Property Name Value
Molecular Formula C23H20Cl2F2N2O2S
Molecular Weight 497.39
AlogP 5.51
Hydrogen Bond Acceptor 3.0
Hydrogen Bond Donor 0.0
Number of Rotational Bond 6.0
Polar Surface Area 40.62
Molecular species NEUTRAL
Aromatic Rings 3.0
Heavy Atoms 32.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Cannabinoid CB1 receptor antagonist PubMed PubMed Wikipedia

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Schizophrenia 2 D012559 ClinicalTrials
Alzheimer Disease 1 D000544 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL3545166
EPA CompTox DTXSID50189455
FDA SRS 61S98RLL5I
PubChem 10278470
SureChEMBL SCHEMBL684143
ZINC ZINC000059299699
CONTENTS