| Synonyms: | |
| Status: | Approved (1951) |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| ATC: | V04CX07 |
| UNII: | 70FP3JLY7N |
Structure
| InChI Key | VWLHWLSRQJQWRG-UHFFFAOYSA-O |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C10H16NO+ |
| Molecular Weight | 166.24 |
| AlogP | 1.98 |
| Hydrogen Bond Acceptor | 1.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 2.0 |
| Polar Surface Area | 20.23 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 12.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Hydrolase
|
- | - | - | - | ||
|
Enzyme
Transferase
|
- | - | - | - | 15.42 | |
|
Epigenetic regulator
Eraser
Histone deacetylase
HDAC class IIb
|
- | - | - | - | -11.07-2.6 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Hypotension, Orthostatic | 1 | D007024 | ClinicalTrials |
| Orthostatic Intolerance | 1 | D054971 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 251408 |
| ChEMBL | CHEMBL1104 |
| DrugBank | DB01010 |
| DrugCentral | 988 |
| EPA CompTox | DTXSID4046943 |
| FDA SRS | 70FP3JLY7N |
| Human Metabolome Database | HMDB15145 |
| Guide to Pharmacology | 9073 |
| KEGG | C06976 |
| PDB | EDR |
| PharmGKB | PA449437 |
| PubChem | 3202 |
| SureChEMBL | SCHEMBL34790 |
| ZINC | ZINC000000001341 |
CONTENTS