| Synonyms: | |
| Status: | Phase 2 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 3P4CR02JTD |
Structure
| InChI Key | MXNGYQJJYRVGGJ-QFIPXVFZSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C25H22N2O |
| Molecular Weight | 366.46 |
| AlogP | 5.78 |
| Hydrogen Bond Acceptor | 2.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 5.0 |
| Polar Surface Area | 41.99 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 4.0 |
| Heavy Atoms | 28.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Membrane receptor
Family A G protein-coupled receptor
Peptide receptor (family A GPCR)
Short peptide receptor (family A GPCR)
Neurokinin receptor
|
- | - | - | 18 | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Pulmonary Disease, Chronic Obstructive | 2 | D029424 | ClinicalTrials |
| Asthma | 2 | D001249 | ClinicalTrials |
| Inflammation | 1 | D007249 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL9960 |
| FDA SRS | 3P4CR02JTD |
| PubChem | 25143624 |
| SureChEMBL | SCHEMBL6447341 |
| ZINC | ZINC000002105296 |
CONTENTS