| Synonyms: | |
| Status: | Phase 2 |
| Entry Type: | Unknown |
| Molecule Category: | UNKNOWN |
| UNII: | F2IBD1GMD3 |
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C27H22F2N4O |
| Molecular Weight | 456.5 |
| AlogP | 5.35 |
| Hydrogen Bond Acceptor | 5.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 3.0 |
| Polar Surface Area | 86.17 |
| Molecular species | None |
| Aromatic Rings | 4.0 |
| Heavy Atoms | 34.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| AGONIST | Somatostatin receptor 2 agonist |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Cytochrome P450
Cytochrome P450 family 2
Cytochrome P450 family 2C
Cytochrome P450 2C19
|
- | 5011.87 | - | - | - | |
|
Enzyme
Cytochrome P450
Cytochrome P450 family 2
Cytochrome P450 family 2C
Cytochrome P450 2C9
|
- | 7943.28 | - | - | - | |
|
Membrane receptor
Family A G protein-coupled receptor
Peptide receptor (family A GPCR)
Short peptide receptor (family A GPCR)
Somatostatin receptor
|
0.25-0.2512 | - | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Acromegaly | 3 | D000172 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL4594359 |
| FDA SRS | F2IBD1GMD3 |
| PubChem | 134168328 |
CONTENTS