SELURAMPANEL

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 7WG1MR7DAR

Structure
InChI Key MCECSFFXUPEPDB-UHFFFAOYSA-N
Smile CC(C)c1cc2[nH]c(=O)n(NS(C)(=O)=O)c(=O)c2cc1-c1ccnn1C
InChI
InChI=1S/C16H19N5O4S/c1-9(2)10-8-13-12(7-11(10)14-5-6-17-20(14)3)15(22)21(16(23)18-13)19-26(4,24)25/h5-9,19H,1-4H3,(H,18,23)

Physicochemical Descriptors

Property Name Value
Molecular Formula C16H19N5O4S
Molecular Weight 377.43
AlogP 0.72
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 4.0
Polar Surface Area 118.85
Molecular species NEUTRAL
Aromatic Rings 3.0
Heavy Atoms 26.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Glutamate receptor ionotropic AMPA antagonist PubMed Wikipedia

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Migraine Disorders 2 D008881 ClinicalTrials
Seizures 2 D012640 ClinicalTrials
Epilepsy 2 D004827 ClinicalTrials
Multiple Sclerosis 2 D009103 ClinicalTrials
Tinnitus 2 D014012 ClinicalTrials
Muscle Spasticity 2 D009128 ClinicalTrials
Epilepsy, Reflex 2 D020195 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL3545042
DrugBank DB12367
EPA CompTox DTXSID00238467
FDA SRS 7WG1MR7DAR
PubChem 45381907
SureChEMBL SCHEMBL1660562
ZINC ZINC000116796247
CONTENTS