| Synonyms: | |
| Status: | Phase 1 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 4L1AM42NVA |
Structure
| InChI Key | ISOCDPQFIXDIMS-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C25H28N6O2 |
| Molecular Weight | 444.54 |
| AlogP | 3.41 |
| Hydrogen Bond Acceptor | 7.0 |
| Hydrogen Bond Donor | 3.0 |
| Number of Rotational Bond | 6.0 |
| Polar Surface Area | 91.41 |
| Molecular species | BASE |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 33.0 |
Pharmacology
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Polycythemia Vera | 1 | D011087 | ClinicalTrials |
| Thrombocythemia, Essential | 1 | D013920 | ClinicalTrials |
| Primary Myelofibrosis | 1 | D055728 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL3545328 |
| FDA SRS | 4L1AM42NVA |
| PubChem | 57990869 |
| SureChEMBL | SCHEMBL4379072 |
CONTENTS