| Synonyms: | |
| Status: | Phase 3 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 0A7729F42K |
Structure
| InChI Key | KRTIYQIPSAGSBP-KLAILNCOSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C24H24ClFN2O |
| Molecular Weight | 410.92 |
| AlogP | 6.58 |
| Hydrogen Bond Acceptor | 2.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 4.0 |
| Polar Surface Area | 41.99 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 29.0 |
Pharmacology
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Urinary Bladder Neoplasms | 3 | D001749 | ClinicalTrials |
| Melanoma | 3 | D008545 | ClinicalTrials |
| Carcinoma, Non-Small-Cell Lung | 3 | D002289 | ClinicalTrials |
| Head and Neck Neoplasms | 3 | D006258 | ClinicalTrials |
| Skin Neoplasms | 3 | D012878 | ClinicalTrials |
| Neoplasms | 2 | D009369 | ClinicalTrials |
| Stomach Neoplasms | 2 | D013274 | ClinicalTrials |
| Squamous Cell Carcinoma of Head and Neck | 2 | D000077195 | ClinicalTrials |
| Carcinoma, Hepatocellular | 1 | D006528 | ClinicalTrials |
| Glioblastoma | 1 | D005909 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL4297598 |
| FDA SRS | 0A7729F42K |
| Guide to Pharmacology | 9707 |
| PubChem | 121328278 |
| SureChEMBL | SCHEMBL18826792 |
CONTENTS