Synonyms: | |
Status: | Phase 2 |
Entry Type: | Small molecule |
Molecule Category: | UNKNOWN |
UNII: | 2T6D2HPX7Q |
InChI Key | ADFCQWZHKCXPAJ-GFCCVEGCSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C15H14O3 |
Molecular Weight | 242.27 |
AlogP | 2.82 |
Hydrogen Bond Acceptor | 3.0 |
Hydrogen Bond Donor | 2.0 |
Number of Rotational Bond | 1.0 |
Polar Surface Area | 49.69 |
Molecular species | NEUTRAL |
Aromatic Rings | 2.0 |
Heavy Atoms | 18.0 |
Action | Mechanism of Action | Reference |
---|---|---|
AGONIST | Estrogen receptor beta agonist | Other |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Transcription factor
Nuclear receptor
Nuclear hormone receptor subfamily 3
Nuclear hormone receptor subfamily 3 group C
Nuclear hormone receptor subfamily 3 group C member 4
|
- | 74131 | - | - | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Prostatic Hyperplasia | 2 | D011470 | ClinicalTrials |
Menopause | 2 | D008593 | ClinicalTrials |
Alzheimer Disease | 1 | D000544 | ClinicalTrials |
Breast Neoplasms | 0 | D001943 | ClinicalTrials |
Resources | Reference |
---|---|
ChEBI | 34741 |
ChEMBL | CHEMBL198877 |
DrugBank | DB11674 |
EPA CompTox | DTXSID0022309 |
FDA SRS | 2T6D2HPX7Q |
Human Metabolome Database | HMDB0002209 |
KEGG | C14131 |
SureChEMBL | SCHEMBL43647 |
ZINC | ZINC000000388661 |