TOCILIZUMAB

Search structure
Synonyms:
MRA
Status: Approved (2005)
Entry Type: Antibody
Molecule Category: UKNOWN
ATC: L04AC07
UNII: I031V2H011

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Interleukin-6 receptor alpha subunit inhibitor DailyMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Scleroderma, Systemic 4 D012595 ClinicalTrials
Arthritis, Juvenile 4 D001171 ClinicalTrials
Severe Acute Respiratory Syndrome 3 D045169 ClinicalTrials
Lymphoma, Large B-Cell, Diffuse 3 D016403 ClinicalTrials
Polymyalgia Rheumatica 3 D011111 ClinicalTrials
Takayasu Arteritis 3 D013625 ClinicalTrials
Severe Acute Respiratory Syndrome 3 D045169 ClinicalTrials
Spondylitis, Ankylosing 3 D013167 ClinicalTrials
Fever 2 D005334 ClinicalTrials
Leukemia 2 D007938 ClinicalTrials
Schnitzler Syndrome 2 D019873 ClinicalTrials
Graves Ophthalmopathy 2 D049970 ClinicalTrials
Fibrous Dysplasia of Bone 2 D005357 ClinicalTrials
Pancreatic Neoplasms 2 D010190 ClinicalTrials
Behcet Syndrome 2 D001528 ClinicalTrials
Neuromyelitis Optica 2 D009471 ClinicalTrials
Still's Disease, Adult-Onset 2 D016706 ClinicalTrials
Erdheim-Chester Disease 2 D031249 ClinicalTrials
Polychondritis, Relapsing 2 D011081 ClinicalTrials
Familial Mediterranean Fever 2 D010505 ClinicalTrials
Hypertension, Pulmonary 2 D006976 ClinicalTrials
Leukemia, Myeloid, Acute 2 D015470 ClinicalTrials
Neoplasms 2 D009369 ClinicalTrials
Melanoma 2 D008545 ClinicalTrials
Amyotrophic Lateral Sclerosis 2 D000690 ClinicalTrials
Uveitis 2 D014605 ClinicalTrials
Non-ST Elevated Myocardial Infarction 2 D000072658 ClinicalTrials
Diabetes Mellitus, Type 1 2 D003922 ClinicalTrials
Prostatic Neoplasms 2 D011471 ClinicalTrials
Pneumonia 2 D011014 ClinicalTrials
Pneumonia, Viral 2 D011024 ClinicalTrials
Depressive Disorder, Major 2 D003865 ClinicalTrials
Macrophage Activation Syndrome 2 D055501 ClinicalTrials
Breast Neoplasms 2 D001943 ClinicalTrials
Graft vs Host Disease 2 D006086 ClinicalTrials
Graft vs Host Disease 2 D006086 ClinicalTrials
Lymphohistiocytosis, Hemophagocytic 2 D051359 ClinicalTrials
Castleman Disease 2 D005871 ClinicalTrials
Hematologic Neoplasms 2 D019337 ClinicalTrials
Precursor Cell Lymphoblastic Leukemia-Lymphoma 2 D054198 ClinicalTrials
Glioblastoma 2 D005909 ClinicalTrials
Respiratory Distress Syndrome 2 D012128 ClinicalTrials
Dermatomyositis 2 D003882 ClinicalTrials
Lymphoma 1 D008223 ClinicalTrials
Schizophrenia 1 D012559 ClinicalTrials
Renal Insufficiency, Chronic 1 D051436 ClinicalTrials
HIV Infections 1 D015658 ClinicalTrials
Leukemia, Lymphocytic, Chronic, B-Cell 1 D015451 ClinicalTrials
Carcinoma, Hepatocellular 1 D006528 ClinicalTrials
Multiple Myeloma 1 D009101 ClinicalTrials
Lymphoma, Non-Hodgkin 1 D008228 ClinicalTrials
Uveitis, Intermediate 1 D015867 ClinicalTrials
Uveitis, Posterior 1 D015866 ClinicalTrials
Leukemia, Biphenotypic, Acute 1 D015456 ClinicalTrials
Lymphoma, Follicular 1 D008224 ClinicalTrials
Carcinoma, Non-Small-Cell Lung 1 D002289 ClinicalTrials
Urinary Bladder Neoplasms 1 D001749 ClinicalTrials
Colorectal Neoplasms 1 D015179 ClinicalTrials
Ovarian Neoplasms 1 D010051 ClinicalTrials
Lymphoma, Follicular 1 D008224 ClinicalTrials
Liver Neoplasms 1 D008113 ClinicalTrials
Urinary Bladder Neoplasms 1 D001749 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL1237022
FDA SRS I031V2H011
CONTENTS