| Synonyms: | |
| Status: | Phase 3 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | IC58Q2EHPJ |
Structure
| InChI Key | ZGCYVRNZWGUXNQ-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C20H26N4O4 |
| Molecular Weight | 386.45 |
| AlogP | 2.28 |
| Hydrogen Bond Acceptor | 7.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 9.0 |
| Polar Surface Area | 108.59 |
| Molecular species | BASE |
| Aromatic Rings | 2.0 |
| Heavy Atoms | 28.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| ANTAGONIST | Mu opioid receptor antagonist | Other |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Constipation | 3 | D003248 | ClinicalTrials |
| Kidney Diseases | 1 | D007674 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL3039511 |
| DrugBank | DB12464 |
| EPA CompTox | DTXSID90217963 |
| FDA SRS | IC58Q2EHPJ |
| SureChEMBL | SCHEMBL1462219 |
| ZINC | ZINC000038896576 |
CONTENTS