| Synonyms: | |
| Status: | Phase 3 |
| Entry Type: | Small molecule |
| Molecule Category: | UKNOWN |
| UNII: | 0829J8133H |
Structure
| InChI Key | XGOYIMQSIKSOBS-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C17H14O4 |
| Molecular Weight | 282.3 |
| AlogP | 3.19 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 2.0 |
| Polar Surface Area | 67.51 |
| Molecular species | ACID |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 21.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Unclassified protein
|
35200 | - | 130-130 | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Carcinoma, Non-Small-Cell Lung | 3 | D002289 | ClinicalTrials |
| Urinary Bladder Neoplasms | 2 | D001749 | ClinicalTrials |
| Prostatic Neoplasms, Castration-Resistant | 2 | D064129 | ClinicalTrials |
| Lung Neoplasms | 2 | D008175 | ClinicalTrials |
| Neoplasms | 1 | D009369 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 75934 |
| ChEMBL | CHEMBL71263 |
| DrugBank | DB06235 |
| EPA CompTox | DTXSID2040949 |
| FDA SRS | 0829J8133H |
| PDB | 1YE |
| SureChEMBL | SCHEMBL111183 |
| ZINC | ZINC000003777432 |
CONTENTS