CAPROMORELIN

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 0MQ44VUN84

Structure
InChI Key KVLLHLWBPNCVNR-SKCUWOTOSA-N
Smile CN1N=C2CCN(C(=O)[C@@H](COCc3ccccc3)NC(=O)C(C)(C)N)C[C@@]2(Cc2ccccc2)C1=O
InChI
InChI=1S/C28H35N5O4/c1-27(2,29)25(35)30-22(18-37-17-21-12-8-5-9-13-21)24(34)33-15-14-23-28(19-33,26(36)32(3)31-23)16-20-10-6-4-7-11-20/h4-13,22H,14-19,29H2,1-3H3,(H,30,35)/t22-,28-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C28H35N5O4
Molecular Weight 505.62
AlogP 1.71
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 9.0
Polar Surface Area 117.33
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 37.0

Pharmacology

Action Mechanism of Action Reference
AGONIST Ghrelin receptor agonist PubMed PubMed PubMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) Short peptide receptor (family A GPCR) GRP-related receptor
1-1 20-3000 - 7 -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Aging 2 D000375 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL113313
DrugBank DB15205
EPA CompTox DTXSID5057886
FDA SRS 0MQ44VUN84
SureChEMBL SCHEMBL1147592
ZINC ZINC000004393135
CONTENTS