LEVOBUPIVACAINE HYDROCHLORIDE

Search structure
Synonyms:
Status: Approved (1999)
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: J998RDZ51I

Structure
InChI Key SIEYLFHKZGLBNX-NTISSMGPSA-N
Smile CCCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C.Cl
InChI
InChI=1S/C18H28N2O.ClH/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3;/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21);1H/t16-;/m0./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C18H29ClN2O
Molecular Weight 324.9
AlogP 3.9
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 5.0
Polar Surface Area 32.34
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 21.0

Pharmacology

Action Mechanism of Action Reference
BLOCKER Sodium channel protein type IV alpha subunit blocker PubMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Ion channel Voltage-gated ion channel Potassium channels Voltage-gated potassium channel
- 13000-83000 - - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Pregnancy 3 D011247 ClinicalTrials
Pain 3 D010146 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEBI 31772
ChEMBL CHEMBL1200749
EPA CompTox DTXSID9046071
FDA SRS J998RDZ51I
SureChEMBL SCHEMBL34174
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