RISUTEGANIB

Search structure
Synonyms:
Status: Phase 2
Entry Type: Protein
Molecule Category: UKNOWN
UNII: 123DNA66IA

Structure
InChI Key MYZAXBZLEILEBR-RVFOSREFSA-N
Smile C[C@@H](O)[C@H](NC(=O)[C@H](CS(=O)(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)CN)C(=O)N1CCC[C@H]1C(=O)O
InChI
InChI=1S/C22H39N9O11S/c1-11(32)17(20(37)31-7-3-5-14(31)21(38)39)30-19(36)13(10-43(40,41)42)29-16(34)9-27-18(35)12(28-15(33)8-23)4-2-6-26-22(24)25/h11-14,17,32H,2-10,23H2,1H3,(H,27,35)(H,28,33)(H,29,34)(H,30,36)(H,38,39)(H4,24,25,26)(H,40,41,42)/t11-,12+,13+,14+,17+/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C22H39N9O11S
Molecular Weight 637.67
AlogP -5.88
Hydrogen Bond Acceptor 11.0
Hydrogen Bond Donor 11.0
Number of Rotational Bond 17.0
Polar Surface Area 336.53
Molecular species ZWITTERION
Aromatic Rings 0.0
Heavy Atoms 43.0

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Macular Degeneration 2 D008268 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL4297529
DrugBank DB14911
FDA SRS 123DNA66IA
SureChEMBL SCHEMBL19410626
CONTENTS