| Synonyms: | |
| Status: | Phase 3 |
| Entry Type: | Small molecule |
| Molecule Category: | UKNOWN |
| UNII: | 27JT06E6GR |
Structure
| InChI Key | NTNWOCRCBQPEKQ-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C7H16N4O2 |
| Molecular Weight | 188.23 |
| AlogP | -1.08 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 5.0 |
| Number of Rotational Bond | 5.0 |
| Polar Surface Area | 111.23 |
| Molecular species | ZWITTERION |
| Aromatic Rings | 0.0 |
| Heavy Atoms | 13.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
|
- | 2-27000 | - | 400-400 | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Anemia | 2 | D000740 | ClinicalTrials |
| Hyperlipidemias | 2 | D006949 | ClinicalTrials |
| Anemia, Sickle Cell | 2 | D000755 | ClinicalTrials |
| Breast Neoplasms | 2 | D001943 | ClinicalTrials |
| Sarcopenia | 1 | D055948 | ClinicalTrials |
| HIV Infections | 1 | D015658 | ClinicalTrials |
| Hypoxia | 1 | D000860 | ClinicalTrials |
| Cerebral Arterial Diseases | 0 | D002539 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 124959 |
| ChEMBL | CHEMBL256147 |
| DrugBank | DB11815 |
| EPA CompTox | DTXSID3040560 |
| FDA SRS | 27JT06E6GR |
| Human Metabolome Database | HMDB0029416 |
| KEGG | C03884 |
| PDB | NMM |
| SureChEMBL | SCHEMBL315843 |
| ZINC | ZINC000001529776 |
CONTENTS