| Synonyms: | |
| Status: | Phase 2 |
| Entry Type: | Small molecule |
| Molecule Category: | UKNOWN |
| UNII: | 9TMU325RK3 |
Structure
| InChI Key | FWUQWDCOOWEXRY-ZDUSSCGKSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C13H14N2 |
| Molecular Weight | 198.27 |
| AlogP | 2.32 |
| Hydrogen Bond Acceptor | 2.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 3.0 |
| Polar Surface Area | 38.91 |
| Molecular species | BASE |
| Aromatic Rings | 2.0 |
| Heavy Atoms | 15.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Ion channel
Ligand-gated ion channel
Ionotropic glutamate receptor
NMDA receptor
|
- | - | - | 14000 | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Depressive Disorder, Major | 2 | D003865 | ClinicalTrials |
| Depressive Disorder | 2 | D003866 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL467084 |
| DrugBank | DB11889 |
| FDA SRS | 9TMU325RK3 |
| Guide to Pharmacology | 7681 |
| SureChEMBL | SCHEMBL1422817 |
| ZINC | ZINC000000006163 |
CONTENTS