SUCCINIC ACID

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: AB6MNQ6J6L

Structure
InChI Key KDYFGRWQOYBRFD-UHFFFAOYSA-N
Smile O=C(O)CCC(=O)O
InChI
InChI=1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

Physicochemical Descriptors

Property Name Value
Molecular Formula C4H6O4
Molecular Weight 118.09
AlogP -0.06
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 3.0
Polar Surface Area 74.6
Molecular species ACID
Aromatic Rings 0.0
Heavy Atoms 8.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Oxidoreductase
- 3000-510000 - - -
Enzyme Transferase
- - - - 4.61
Epigenetic regulator Eraser Histone deacetylase HDAC class IIb
- - - - -2.17-18.2
Epigenetic regulator Eraser Lysine demethylase Jumonji domain-containing
- 1400000-1400000 - - -
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Carboxylic acid receptor Succinate receptor
2041.74-9549.93 - - 199526.23-630957.34 -
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC13 family of sodium-dependent sulphate/carboxylate transporters
107000 - - - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Diabetic Neuropathies 3 D003929 ClinicalTrials
Stroke 3 D020521 ClinicalTrials

Cross References

Resources Reference
ChEBI 15741
ChEMBL CHEMBL576
DrugBank DB00139
DrugCentral 2487
EPA CompTox DTXSID6023602
FDA SRS AB6MNQ6J6L
Human Metabolome Database HMDB00254
Guide to Pharmacology 3637
KEGG C00042
PDB SIN
PubChem 21952380
SureChEMBL SCHEMBL829
ZINC ZINC000000895030
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