MOEXIPRIL HYDROCHLORIDE

Search structure
Synonyms:
Status: Approved (1995)
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: Q1UMG3UH45

Structure
InChI Key JXRAXHBVZQZSIC-JKVLGAQCSA-N
Smile CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1Cc2cc(OC)c(OC)cc2C[C@H]1C(=O)O.Cl
InChI
InChI=1S/C27H34N2O7.ClH/c1-5-36-27(33)21(12-11-18-9-7-6-8-10-18)28-17(2)25(30)29-16-20-15-24(35-4)23(34-3)14-19(20)13-22(29)26(31)32;/h6-10,14-15,17,21-22,28H,5,11-13,16H2,1-4H3,(H,31,32);1H/t17-,21-,22-;/m0./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C27H35ClN2O7
Molecular Weight 535.04
AlogP 2.58
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 11.0
Polar Surface Area 114.4
Molecular species ACID
Aromatic Rings 2.0
Heavy Atoms 36.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Angiotensin-converting enzyme inhibitor
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Transferase
- - - - 0.6292
Epigenetic regulator Eraser Histone deacetylase HDAC class IIb
- - - - -3.25--0.68

Indications

Mesh Heading Maximum Phase Mesh ID Reference

Related Entries

Scaffolds

Cross References

Resources Reference
ChEBI 6961
ChEMBL CHEMBL1200534
EPA CompTox DTXSID7044267
FDA SRS Q1UMG3UH45
PubChem 54889
SureChEMBL SCHEMBL40877
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