RALMITARONT

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: QA8MW1Q80P

Structure
InChI Key XHHXGKRFUPEPFM-OAHLLOKOSA-N
Smile CCc1[nH]nc(C(=O)Nc2ccc([C@H]3CNCCO3)cc2)c1C
InChI
InChI=1S/C17H22N4O2/c1-3-14-11(2)16(21-20-14)17(22)19-13-6-4-12(5-7-13)15-10-18-8-9-23-15/h4-7,15,18H,3,8-10H2,1-2H3,(H,19,22)(H,20,21)/t15-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C17H22N4O2
Molecular Weight 314.39
AlogP 2.19
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 4.0
Polar Surface Area 79.04
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 23.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Ion channel Voltage-gated ion channel Potassium channels Voltage-gated potassium channel
- 216600-216600 - - -
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Trace amine receptor
58.5-395 - - - -
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC06 neurotransmitter transporter family
- - - 27530-27530 -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Psychotic Disorders 2 D011618 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL4594376
FDA SRS QA8MW1Q80P
SureChEMBL SCHEMBL19356836
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