Synonyms: | |
Status: | Approved (2020) |
Entry Type: | Small molecule |
Molecule Category: | UKNOWN |
UNII: | CEGM9YBNGD |
InChI Key | XIIOFHFUYBLOLW-UHFFFAOYSA-N |
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Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C29H31N7O3 |
Molecular Weight | 525.61 |
AlogP | 3.28 |
Hydrogen Bond Acceptor | 10.0 |
Hydrogen Bond Donor | 1.0 |
Number of Rotational Bond | 8.0 |
Polar Surface Area | 112.04 |
Molecular species | NEUTRAL |
Aromatic Rings | 4.0 |
Heavy Atoms | 39.0 |
Action | Mechanism of Action | Reference |
---|---|---|
INHIBITOR | Coiled-coil domain-containing protein 6/Tyrosine-protein kinase receptor RET inhibitor | FDA |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Carcinoma, Non-Small-Cell Lung | 4 | D002289 | ClinicalTrials |
Thyroid Neoplasms | 4 | D013964 | FDA |
Resources | Reference |
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ChEMBL | CHEMBL4559134 |
FDA SRS | CEGM9YBNGD |
Guide to Pharmacology | 10318 |
SureChEMBL | SCHEMBL20071478 |