RELDESEMTIV

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 4S0HBYW6QE

Structure
InChI Key MQXWPWOCXGARRK-HJGJAMNPSA-N
Smile NC(=O)c1ccn(-c2cnc(NC[C@]3(c4ncccc4F)C[C@H](F)C3)nc2)c1
InChI
InChI=1S/C19H18F2N6O/c20-13-6-19(7-13,16-15(21)2-1-4-23-16)11-26-18-24-8-14(9-25-18)27-5-3-12(10-27)17(22)28/h1-5,8-10,13H,6-7,11H2,(H2,22,28)(H,24,25,26)/t13-,19-

Physicochemical Descriptors

Property Name Value
Molecular Formula C19H18F2N6O
Molecular Weight 384.39
AlogP 2.38
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 6.0
Polar Surface Area 98.72
Molecular species NEUTRAL
Aromatic Rings 3.0
Heavy Atoms 28.0

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Amyotrophic Lateral Sclerosis 3 D000690 ClinicalTrials
Pulmonary Disease, Chronic Obstructive 2 D029424 ClinicalTrials
Muscular Atrophy, Spinal 2 D009134 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL4297600
DrugBank DB15256
FDA SRS 4S0HBYW6QE
SureChEMBL SCHEMBL12288022
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