ILEPATRIL

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UKNOWN
UNII: 5N1YAP5FCM

Structure
InChI Key FXKFFTMLFPWYFH-RDGPPVDQSA-N
Smile CC(=O)S[C@H](C(=O)N[C@H]1Cc2ccccc2[C@H]2CCC[C@@H](C(=O)O)N2C1=O)C(C)C
InChI
InChI=1S/C22H28N2O5S/c1-12(2)19(30-13(3)25)20(26)23-16-11-14-7-4-5-8-15(14)17-9-6-10-18(22(28)29)24(17)21(16)27/h4-5,7-8,12,16-19H,6,9-11H2,1-3H3,(H,23,26)(H,28,29)/t16-,17+,18-,19-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C22H28N2O5S
Molecular Weight 432.54
AlogP 2.54
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 5.0
Polar Surface Area 103.78
Molecular species ACID
Aromatic Rings 1.0
Heavy Atoms 30.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Angiotensin-converting enzyme inhibitor PubMed PubMed PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Hypertension 2 D006973 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL3187812
DrugBank DB06604
EPA CompTox DTXSID7047356
FDA SRS 5N1YAP5FCM
SureChEMBL SCHEMBL171139
ZINC ZINC000003928701
CONTENTS