ESMOLOL HYDROCHLORIDE

Search structure
Synonyms:
Status: Approved (1986)
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: V05260LC8D

Structure
InChI Key GEKNCWBANDDJJL-UHFFFAOYSA-N
Smile COC(=O)CCc1ccc(OCC(O)CNC(C)C)cc1.Cl
InChI
InChI=1S/C16H25NO4.ClH/c1-12(2)17-10-14(18)11-21-15-7-4-13(5-8-15)6-9-16(19)20-3;/h4-5,7-8,12,14,17-18H,6,9-11H2,1-3H3;1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C16H26ClNO4
Molecular Weight 331.84
AlogP 1.53
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 9.0
Polar Surface Area 67.79
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 21.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Beta-1 adrenergic receptor antagonist DailyMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Diabetic Foot 3 D017719 ClinicalTrials
Shock, Septic 2 D012772 ClinicalTrials
Ovarian Cysts 1 D010048 ClinicalTrials
Cognitive Dysfunction 1 D060825 ClinicalTrials

Cross References

Resources Reference
ChEBI 4857
ChEMBL CHEMBL1201115
EPA CompTox DTXSID7049003
FDA SRS V05260LC8D
SureChEMBL SCHEMBL41086
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