FIRIBASTAT

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 638KY4573I

Structure
InChI Key HJPXZXVKLGEMGP-YUMQZZPRSA-N
Smile N[C@@H](CCS(=O)(=O)O)CSSC[C@@H](N)CCS(=O)(=O)O
InChI
InChI=1S/C8H20N2O6S4/c9-7(1-3-19(11,12)13)5-17-18-6-8(10)2-4-20(14,15)16/h7-8H,1-6,9-10H2,(H,11,12,13)(H,14,15,16)/t7-,8-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C8H20N2O6S4
Molecular Weight 368.52
AlogP -0.42
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 4.0
Number of Rotational Bond 11.0
Polar Surface Area 160.78
Molecular species ZWITTERION
Aromatic Rings 0.0
Heavy Atoms 20.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Aminopeptidase A inhibitor PubMed PubMed PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Hypertension 3 D006973 ClinicalTrials
Myocardial Infarction 2 D009203 ClinicalTrials
Heart Failure 2 D006333 ClinicalTrials
Essential Hypertension 2 D000075222 ClinicalTrials
Renal Insufficiency 1 D051437 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL4297511
DrugBank DB13107
FDA SRS 638KY4573I
SureChEMBL SCHEMBL1694944
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