| Synonyms: | |
| Status: | Approved (2023) |
| Entry Type: | Small molecule |
| Molecule Category: | UKNOWN |
Structure
| InChI Key | FWZAWAUZXYCBKZ-NSHDSACASA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C22H21F4N5O3 |
| Molecular Weight | 479.43 |
| AlogP | 3.43 |
| Hydrogen Bond Acceptor | 6.0 |
| Hydrogen Bond Donor | 3.0 |
| Number of Rotational Bond | 7.0 |
| Polar Surface Area | 125.26 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 34.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | Tyrosine-protein kinase BTK inhibitor | Other |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Leukemia, Lymphocytic, Chronic, B-Cell | 3 | D015451 | ClinicalTrials |
| Lymphoma, Mantle-Cell | 3 | D020522 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL4650485 |
CONTENTS