DANAVOREXTON

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Synonyms:	Danavorexton Tak-925 TAK-925
Status:	Phase 1
Entry Type:	Small molecule
Molecule Category:	UKNOWN

Structure


InChI Key	UXZAJSZFFARTEI-YRPNKDGESA-N
Smile	COC(=O)N1CCC[C@H](NS(C)(=O)=O)[C@@H]1CO[C@H]1CC[C@@H](c2ccccc2)CC1
InChI	InChI=1S/C21H32N2O5S/c1-27-21(24)23-14-6-9-19(22-29(2,25)26)20(23)15-28-18-12-10-17(11-13-18)16-7-4-3-5-8-16/h3-5,7-8,17-20,22H,6,9-15H2,1-2H3/t17-,18+,19-,20-/m0/s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C21H32N2O5S
Molecular Weight	424.56
AlogP	2.88
Hydrogen Bond Acceptor	5.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	6.0
Polar Surface Area	84.94
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	29.0

Indications

Mesh Heading	Maximum Phase	Mesh ID	Reference
Narcolepsy	1	D009290	ClinicalTrials
Sleep Apnea, Obstructive	1	D020181	ClinicalTrials
Narcolepsy	1	D009290	ClinicalTrials
Idiopathic Hypersomnia	1	D020177	ClinicalTrials

Cross References

Resources	Reference
ChEMBL	CHEMBL4650341

CONTENTS