Synonyms: | |
Status: | Phase 2 |
Entry Type: | Small molecule |
Molecule Category: | UKNOWN |
InChI Key | DCGDPJCUIKLTDU-QWQRMKEZSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C23H22F4N6O2 |
Molecular Weight | 490.46 |
AlogP | 5.12 |
Hydrogen Bond Acceptor | 7.0 |
Hydrogen Bond Donor | 1.0 |
Number of Rotational Bond | 6.0 |
Polar Surface Area | 93.13 |
Molecular species | NEUTRAL |
Aromatic Rings | 3.0 |
Heavy Atoms | 35.0 |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Enzyme
Oxidoreductase
|
- | 73-316 | - | - | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Glioma | 2 | D005910 | ClinicalTrials |
Leukemia, Myeloid, Acute | 1 | D015470 | ClinicalTrials |
Neoplasms | 1 | D009369 | ClinicalTrials |
Resources | Reference |
---|---|
ChEMBL | CHEMBL4167360 |