| Synonyms: | |
| Status: | Phase 2 |
| Entry Type: | Unknown |
| Molecule Category: | UNKNOWN |
| UNII: | 25J7VT36F9 |
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C14H17FN2O2 |
| Molecular Weight | 264.3 |
| AlogP | 1.57 |
| Hydrogen Bond Acceptor | 2.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 2.0 |
| Polar Surface Area | 49.41 |
| Molecular species | None |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 19.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Transferase
|
- | - | - | - | 5.248-26.09 | |
|
Epigenetic regulator
Eraser
Histone deacetylase
HDAC class IIb
|
- | - | - | - | -1.75-13.66 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Alzheimer Disease | 2 | D000544 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL4802206 |
| FDA SRS | 25J7VT36F9 |
CONTENTS