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Therapeutic Area
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CARDIOVASCULAR (45)
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DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
6532
MOXAVERINE
2
Small molecule
Investigational
Unknown
Unknown
Digestive System Diseases; Ischemia
Unknown
MOXAVERINE
×
Maximum Phase:
2
First Approval:
None
UNII:
P3P08Y1XJ4
Molecule Type:
Small molecule
Molecular Formula:
C20H21NO2
Molecular Weight:
307.39
AlogP:
4.41
PSA:
31.35
HBD:
0.0
HBA:
#RotB:
5.0
Source:
YM-543
2
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
Sodium/glucose cotransporter 2 inhibitor
YM-543
×
Maximum Phase:
2
First Approval:
None
UNII:
KA83KI0EO9
Molecule Type:
Small molecule
Molecular Formula:
C28H37NO7
Molecular Weight:
499.6
AlogP:
1.6
PSA:
110.38
HBD:
5.0
HBA:
#RotB:
4.0
Source:
AZD0328
2
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease; Schizophrenia
Neuronal acetylcholine receptor protein alpha-7 subunit agonist
AZD0328
×
Maximum Phase:
2
First Approval:
None
UNII:
2B218X5QIY
Molecule Type:
Small molecule
Molecular Formula:
C13H16N2O
Molecular Weight:
216.28
AlogP:
1.48
PSA:
25.36
HBD:
0.0
HBA:
#RotB:
0.0
Source:
AVADOMIDE
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Hepatocellular; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Renal Insufficiency; Melanoma
Unknown
AVADOMIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
28DZS29F59
Molecule Type:
Small molecule
Molecular Formula:
C14H14N4O3
Molecular Weight:
286.29
AlogP:
0.26
PSA:
107.08
HBD:
2.0
HBA:
#RotB:
1.0
Source:
EMIVIRINE
2
Small molecule
Investigational
Unknown
Unknown
HIV Infections
Human immunodeficiency virus type 1 reverse transcriptase inhibitor
EMIVIRINE
×
Maximum Phase:
2
First Approval:
None
UNII:
X87G8IX72O
Molecule Type:
Small molecule
Molecular Formula:
C17H22N2O3
Molecular Weight:
302.37
AlogP:
2.24
PSA:
64.09
HBD:
1.0
HBA:
#RotB:
6.0
Source:
CK-2127107
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
CK-2127107
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
INDISULAM
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Stomach Neoplasms; Breast Neoplasms; Carcinoma, Renal Cell; Colorectal Neoplasms; Leukemia; Melanoma
Unknown
INDISULAM
×
Maximum Phase:
2
First Approval:
None
UNII:
WJ98J3NM90
Molecule Type:
Small molecule
Molecular Formula:
C14H12ClN3O4S2
Molecular Weight:
385.85
AlogP:
2.27
PSA:
122.12
HBD:
3.0
HBA:
#RotB:
4.0
Source:
METHYLINOSITOL
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
METHYLINOSITOL
×
Maximum Phase:
2
First Approval:
None
UNII:
TF9HZN9T0M
Molecule Type:
Small molecule
Molecular Formula:
C7H14O6
Molecular Weight:
194.18
AlogP:
-3.18
PSA:
110.38
HBD:
5.0
HBA:
#RotB:
1.0
Source:
LUTEOLIN
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
LUTEOLIN
×
Maximum Phase:
2
First Approval:
None
UNII:
KUX1ZNC9J2
Molecule Type:
Small molecule
Molecular Formula:
C15H10O6
Molecular Weight:
286.24
AlogP:
2.28
PSA:
111.13
HBD:
4.0
HBA:
#RotB:
1.0
Source:
GOSSYPOL ACETIC ACID
2
Small molecule
Investigational
Unknown
Unknown
Central Nervous System Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Multiple Myeloma; Adrenal Cortex Neoplasms; Gliosarcoma; Small Cell Lung Carcinoma
Unknown
GOSSYPOL ACETIC ACID
×
Maximum Phase:
2
First Approval:
None
UNII:
S7RL72610R
Molecule Type:
Small molecule
Molecular Formula:
C42H42O14
Molecular Weight:
770.78
AlogP:
7.7
PSA:
191.94
HBD:
0.0
HBA:
#RotB:
11.0
Source:
ORTATAXEL
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Renal Cell; Glioblastoma; Kidney Neoplasms; Lung Neoplasms; Lymphoma
Unknown
ORTATAXEL
×
Maximum Phase:
2
First Approval:
None
UNII:
8H61Y4E29N
Molecule Type:
Small molecule
Molecular Formula:
C44H57NO17
Molecular Weight:
871.93
AlogP:
3.66
PSA:
245.82
HBD:
3.0
HBA:
#RotB:
10.0
Source:
VENGLUSTAT MALATE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
VENGLUSTAT MALATE
×
Maximum Phase:
2
First Approval:
None
UNII:
94855LQZ8D
Molecule Type:
Small molecule
Molecular Formula:
C24H30FN3O7S
Molecular Weight:
523.58
AlogP:
4.0
PSA:
54.46
HBD:
1.0
HBA:
#RotB:
4.0
Source:
RELMAPIRAZIN
2
Small molecule
Investigational
Unknown
Unknown
Acute Kidney Injury
Unknown
RELMAPIRAZIN
×
Maximum Phase:
2
First Approval:
None
UNII:
Q3UQB8PQ6H
Molecule Type:
Small molecule
Molecular Formula:
C12H16N6O8
Molecular Weight:
372.29
AlogP:
-4.01
PSA:
251.08
HBD:
8.0
HBA:
#RotB:
8.0
Source:
GSK-2269557
2
Small molecule
Investigational
Unknown
Unknown
Asthma; Pulmonary Disease, Chronic Obstructive
PI3-kinase p110-delta subunit inhibitor
GSK-2269557
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
OLCEGEPANT
2
Small molecule
Investigational
Unknown
Unknown
Migraine Disorders
Calcitonin gene-related peptide type 1 receptor antagonist
OLCEGEPANT
×
Maximum Phase:
2
First Approval:
None
UNII:
WOA5J8TX6M
Molecule Type:
Small molecule
Molecular Formula:
C38H47Br2N9O5
Molecular Weight:
869.66
AlogP:
4.41
PSA:
176.47
HBD:
5.0
HBA:
#RotB:
12.0
Source:
BALICATIB
2
Small molecule
Investigational
Unknown
Unknown
Osteoarthritis; Osteoporosis
Cathepsin K inhibitor
BALICATIB
×
Maximum Phase:
2
First Approval:
None
UNII:
E00MVC7O57
Molecule Type:
Small molecule
Molecular Formula:
C23H33N5O2
Molecular Weight:
411.55
AlogP:
2.29
PSA:
88.47
HBD:
2.0
HBA:
#RotB:
7.0
Source:
CAMPTOTHECIN-20-O-PROPIONATE
2
Small molecule
Investigational
Unknown
Unknown
Lymphoma; Neoplasms; Small Cell Lung Carcinoma
DNA topoisomerase I inhibitor
CAMPTOTHECIN-20-O-PROPIONATE
×
Maximum Phase:
2
First Approval:
None
UNII:
4S145C552U
Molecule Type:
Small molecule
Molecular Formula:
C23H20N2O5
Molecular Weight:
404.42
AlogP:
3.04
PSA:
87.49
HBD:
0.0
HBA:
#RotB:
3.0
Source:
LY-295501
2
Small molecule
Investigational
Unknown
Unknown
Fallopian Tube Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms
Unknown
LY-295501
×
Maximum Phase:
2
First Approval:
None
UNII:
240Y4YO0TN
Molecule Type:
Small molecule
Molecular Formula:
C15H12Cl2N2O4S
Molecular Weight:
387.24
AlogP:
3.44
PSA:
84.5
HBD:
2.0
HBA:
#RotB:
3.0
Source:
PALMIDROL
2
Small molecule
Investigational
Unknown
Unknown
Tourette Syndrome
Unknown
PALMIDROL
×
Maximum Phase:
2
First Approval:
None
UNII:
6R8T1UDM3V
Molecule Type:
Small molecule
Molecular Formula:
C18H37NO2
Molecular Weight:
299.5
AlogP:
4.58
PSA:
49.33
HBD:
2.0
HBA:
#RotB:
16.0
Source:
SARCOSINE
2
Small molecule
Investigational
Unknown
Unknown
Depressive Disorder, Major; Schizophrenia
Unknown
SARCOSINE
×
Maximum Phase:
2
First Approval:
None
UNII:
Z711V88R5F
Molecule Type:
Small molecule
Molecular Formula:
C3H7NO2
Molecular Weight:
89.09
AlogP:
-0.71
PSA:
49.33
HBD:
2.0
HBA:
#RotB:
2.0
Source:
GOLOTIMOD
2
Small molecule
Investigational
Unknown
Unknown
Hepatitis C, Chronic; Stomatitis
Unknown
GOLOTIMOD
×
Maximum Phase:
2
First Approval:
None
UNII:
637C487Y09
Molecule Type:
Small molecule
Molecular Formula:
C16H19N3O5
Molecular Weight:
333.34
AlogP:
0.47
PSA:
145.51
HBD:
5.0
HBA:
#RotB:
8.0
Source:
IOWH-032
2
Small molecule
Investigational
Unknown
Unknown
Digestive System Diseases
Unknown
IOWH-032
×
Maximum Phase:
2
First Approval:
None
UNII:
8Y3GDT6YWV
Molecule Type:
Small molecule
Molecular Formula:
C22H15Br2N3O4
Molecular Weight:
545.19
AlogP:
5.69
PSA:
97.48
HBD:
2.0
HBA:
#RotB:
6.0
Source:
BI 44370 TA
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BI 44370 TA
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
(+)-EPICATECHIN
2
Small molecule
Investigational
Unknown
Unknown
Muscular Dystrophy, Duchenne; Prediabetic State; Friedreich Ataxia; Hypertension
Unknown
(+)-EPICATECHIN
×
Maximum Phase:
2
First Approval:
None
UNII:
LD6B6TT8Q5
Molecule Type:
Small molecule
Molecular Formula:
C15H14O6
Molecular Weight:
290.27
AlogP:
1.55
PSA:
110.38
HBD:
5.0
HBA:
#RotB:
1.0
Source:
CHOLESTEROL
2
Small molecule
Investigational
Unknown
Unknown
Asperger Syndrome; Autistic Disorder; Head and Neck Neoplasms; Porokeratosis; Smith-Lemli-Opitz Syndrome
Unknown
CHOLESTEROL
×
Maximum Phase:
2
First Approval:
None
UNII:
97C5T2UQ7J
Molecule Type:
Small molecule
Molecular Formula:
C27H46O
Molecular Weight:
386.66
AlogP:
7.39
PSA:
20.23
HBD:
1.0
HBA:
#RotB:
5.0
Source:
TNP-2092
2
Small molecule
Investigational
Unknown
Unknown
Infections; Gram-Positive Bacterial Infections
Bacterial DNA-directed RNA polymerase inhibitor
TNP-2092
×
Maximum Phase:
2
First Approval:
None
UNII:
W2P7EF7O6O
Molecule Type:
Small molecule
Molecular Formula:
C65H81FN6O15
Molecular Weight:
1205.39
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
PCI-27483
2
Small molecule
Investigational
Unknown
Unknown
Pancreatic Neoplasms
Coagulation factor VII inhibitor
PCI-27483
×
Maximum Phase:
2
First Approval:
None
UNII:
6073LCU8U9
Molecule Type:
Small molecule
Molecular Formula:
C26H24N6O9S
Molecular Weight:
596.58
AlogP:
0.83
PSA:
282.87
HBD:
9.0
HBA:
#RotB:
10.0
Source:
CYTOSINE
2
Small molecule
Investigational
Unknown
Unknown
Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Unknown
CYTOSINE
×
Maximum Phase:
2
First Approval:
None
UNII:
8J337D1HZY
Molecule Type:
Small molecule
Molecular Formula:
C4H5N3O
Molecular Weight:
111.1
AlogP:
-0.65
PSA:
71.77
HBD:
2.0
HBA:
#RotB:
0.0
Source:
PIROMELATINE
2
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease; Sleep Initiation and Maintenance Disorders
Melatonin receptor agonist
PIROMELATINE
×
Maximum Phase:
2
First Approval:
None
UNII:
S3UN2146K9
Molecule Type:
Small molecule
Molecular Formula:
C17H16N2O4
Molecular Weight:
312.33
AlogP:
2.1
PSA:
84.33
HBD:
2.0
HBA:
#RotB:
5.0
Source:
SABARUBICIN
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Testicular Neoplasms; Prostatic Neoplasms, Castration-Resistant
Unknown
SABARUBICIN
×
Maximum Phase:
2
First Approval:
None
UNII:
XS499WOZ93
Molecule Type:
Small molecule
Molecular Formula:
C32H37NO13
Molecular Weight:
643.64
AlogP:
-0.13
PSA:
235.53
HBD:
7.0
HBA:
#RotB:
6.0
Source:
L 756423
2
Small molecule
Investigational
Unknown
Unknown
HIV Infections
Unknown
L 756423
×
Maximum Phase:
2
First Approval:
None
UNII:
862SGU1BRL
Molecule Type:
Small molecule
Molecular Formula:
C39H48N4O5
Molecular Weight:
652.84
AlogP:
4.22
PSA:
118.28
HBD:
4.0
HBA:
#RotB:
11.0
Source:
DERSALAZINE
2
Small molecule
Investigational
Unknown
Unknown
Colitis, Ulcerative
Unknown
DERSALAZINE
×
Maximum Phase:
2
First Approval:
None
UNII:
WS1IH75AJT
Molecule Type:
Small molecule
Molecular Formula:
C36H33N5O4
Molecular Weight:
599.69
AlogP:
7.53
PSA:
120.38
HBD:
2.0
HBA:
#RotB:
8.0
Source:
DELEOBUVIR SODIUM
2
Small molecule
Investigational
Unknown
Unknown
Hepatitis C, Chronic
Unknown
DELEOBUVIR SODIUM
×
Maximum Phase:
2
First Approval:
None
UNII:
6X4T3L6431
Molecule Type:
Small molecule
Molecular Formula:
C34H32BrN6NaO3
Molecular Weight:
675.56
AlogP:
6.85
PSA:
114.93
HBD:
2.0
HBA:
#RotB:
7.0
Source:
BRILANESTRANT
2
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms
Estrogen receptor alpha antagonist
BRILANESTRANT
×
Maximum Phase:
2
First Approval:
None
UNII:
9MM2R1A06R
Molecule Type:
Small molecule
Molecular Formula:
C26H20ClFN2O2
Molecular Weight:
446.91
AlogP:
6.82
PSA:
65.98
HBD:
2.0
HBA:
#RotB:
6.0
Source:
ENCLOMIPHENE
2
Small molecule
Investigational
Unknown
Unknown
Hypogonadism; Obesity
Estrogen receptor alpha modulator
ENCLOMIPHENE
×
Maximum Phase:
2
First Approval:
None
UNII:
R6D2UI4FLS
Molecule Type:
Small molecule
Molecular Formula:
C26H28ClNO
Molecular Weight:
405.97
AlogP:
6.56
PSA:
12.47
HBD:
0.0
HBA:
#RotB:
9.0
Source:
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Molecular Formula
Molecular Weight
ALogP
PSA