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ENT (5)
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GASTROINTESTINAL (29)
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NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
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PHARMACOLOGY (8)
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RESPIRATORY (42)
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OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
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Level 2
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Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
6532
D-FLUOROMETHYLTYROSINE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
D-FLUOROMETHYLTYROSINE
×
Maximum Phase:
1
First Approval:
None
UNII:
GSM7N3U4J8
Molecule Type:
Small molecule
Molecular Formula:
C10H12FNO3
Molecular Weight:
213.21
AlogP:
0.95
PSA:
72.55
HBD:
2.0
HBA:
#RotB:
5.0
Source:
DWN-12088
1
Small molecule
Investigational
Unknown
Unknown
Idiopathic Pulmonary Fibrosis
Unknown
DWN-12088
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C15H19Cl2N3O
Molecular Weight:
328.24
AlogP:
3.24
PSA:
50.08
HBD:
2.0
HBA:
#RotB:
4.0
Source:
GSK-2018682
1
Small molecule
Investigational
Unknown
Unknown
Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting
Unknown
GSK-2018682
×
Maximum Phase:
1
First Approval:
None
UNII:
NJL503AIJA
Molecule Type:
Small molecule
Molecular Formula:
C22H21ClN4O4
Molecular Weight:
440.89
AlogP:
5.06
PSA:
103.27
HBD:
1.0
HBA:
#RotB:
8.0
Source:
SEVITERONEL
1
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms; Breast Neoplasms, Male; Neoplasms; Prostatic Neoplasms, Castration-Resistant
Unknown
SEVITERONEL
×
Maximum Phase:
1
First Approval:
None
UNII:
8S5OIN36X4
Molecule Type:
Small molecule
Molecular Formula:
C18H17F4N3O3
Molecular Weight:
399.34
AlogP:
4.05
PSA:
80.26
HBD:
2.0
HBA:
#RotB:
7.0
Source:
MK-8245
1
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
Unknown
MK-8245
×
Maximum Phase:
1
First Approval:
None
UNII:
537E7QE8LX
Molecule Type:
Small molecule
Molecular Formula:
C17H16BrFN6O4
Molecular Weight:
467.26
AlogP:
2.36
PSA:
119.4
HBD:
1.0
HBA:
#RotB:
6.0
Source:
BPI-9016
1
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung; Neoplasms
Hepatocyte growth factor receptor inhibitor
BPI-9016
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PKI-179
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
PI3-kinase p110-alpha subunit inhibitor
PKI-179
×
Maximum Phase:
1
First Approval:
None
UNII:
CNN7Y60164
Molecule Type:
Small molecule
Molecular Formula:
C25H28N8O3
Molecular Weight:
488.55
AlogP:
2.78
PSA:
117.63
HBD:
2.0
HBA:
#RotB:
5.0
Source:
INTOPLICINE
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
INTOPLICINE
×
Maximum Phase:
1
First Approval:
None
UNII:
FB2CIN6HMI
Molecule Type:
Small molecule
Molecular Formula:
C21H24N4O
Molecular Weight:
348.45
AlogP:
4.25
PSA:
64.18
HBD:
3.0
HBA:
#RotB:
5.0
Source:
GACYCLIDINE
1
Small molecule
Investigational
Unknown
Unknown
Tinnitus
Unknown
GACYCLIDINE
×
Maximum Phase:
1
First Approval:
None
UNII:
9290ND070R
Molecule Type:
Small molecule
Molecular Formula:
C16H25NS
Molecular Weight:
263.45
AlogP:
4.64
PSA:
3.24
HBD:
0.0
HBA:
#RotB:
2.0
Source:
OSI-930
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Stem cell growth factor receptor inhibitor
OSI-930
×
Maximum Phase:
1
First Approval:
None
UNII:
G1PEG5Q9Y2
Molecule Type:
Small molecule
Molecular Formula:
C22H16F3N3O2S
Molecular Weight:
443.45
AlogP:
6.06
PSA:
63.25
HBD:
2.0
HBA:
#RotB:
6.0
Source:
NIKKOMYCIN Z
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
NIKKOMYCIN Z
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BI 224436
1
Small molecule
Investigational
Unknown
Unknown
HIV Infections
Unknown
BI 224436
×
Maximum Phase:
1
First Approval:
None
UNII:
99A996378Y
Molecule Type:
Small molecule
Molecular Formula:
C27H26N2O4
Molecular Weight:
442.52
AlogP:
5.63
PSA:
81.54
HBD:
1.0
HBA:
#RotB:
4.0
Source:
CI-988
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Cholecystokinin B receptor antagonist
CI-988
×
Maximum Phase:
1
First Approval:
None
UNII:
2637PDX9SI
Molecule Type:
Small molecule
Molecular Formula:
C35H42N4O6
Molecular Weight:
614.74
AlogP:
4.86
PSA:
149.62
HBD:
5.0
HBA:
#RotB:
12.0
Source:
HYDROXYNORKETAMINE, (2R,6R)
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
HYDROXYNORKETAMINE, (2R,6R)
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C12H14ClNO2
Molecular Weight:
239.7
AlogP:
1.61
PSA:
63.32
HBD:
2.0
HBA:
#RotB:
1.0
Source:
HM-71224
1
Small molecule
Investigational
Unknown
Unknown
Arthritis, Rheumatoid
Tyrosine-protein kinase BTK inhibitor
HM-71224
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CFG-920
1
Small molecule
Investigational
Unknown
Unknown
Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant
Unknown
CFG-920
×
Maximum Phase:
1
First Approval:
None
UNII:
UP0K5026VB
Molecule Type:
Small molecule
Molecular Formula:
C14H13ClN4O
Molecular Weight:
288.74
AlogP:
2.89
PSA:
49.33
HBD:
0.0
HBA:
#RotB:
2.0
Source:
COH-29
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
COH-29
×
Maximum Phase:
1
First Approval:
None
UNII:
07802BU06S
Molecule Type:
Small molecule
Molecular Formula:
C22H16N2O5S
Molecular Weight:
420.45
AlogP:
4.55
PSA:
122.91
HBD:
5.0
HBA:
#RotB:
4.0
Source:
BMS-908662
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BMS-908662
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
FK453
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Adenosine A1 receptor antagonist
FK453
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C23H25N3O2
Molecular Weight:
375.47
AlogP:
3.78
PSA:
57.84
HBD:
1.0
HBA:
#RotB:
5.0
Source:
MEPHEDRONE
1
Small molecule
Investigational
Unknown
Unknown
Amphetamine-Related Disorders
Unknown
MEPHEDRONE
×
Maximum Phase:
1
First Approval:
None
UNII:
8BA8T27317
Molecule Type:
Small molecule
Molecular Formula:
C11H15NO
Molecular Weight:
177.25
AlogP:
1.79
PSA:
29.1
HBD:
1.0
HBA:
#RotB:
3.0
Source:
EMODEPSIDE
1
Small molecule
Investigational
Unknown
Unknown
Filariasis
Unknown
EMODEPSIDE
×
Maximum Phase:
1
First Approval:
None
UNII:
YZ647Y5GC9
Molecule Type:
Small molecule
Molecular Formula:
C60H90N6O14
Molecular Weight:
1119.41
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
DIINDOLYLMETHANE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
DIINDOLYLMETHANE
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SELITRECTINIB
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Neurotrophic tyrosine kinase receptor inhibitor
SELITRECTINIB
×
Maximum Phase:
1
First Approval:
None
UNII:
0J45910S3X
Molecule Type:
Small molecule
Molecular Formula:
C20H21FN6O
Molecular Weight:
380.43
AlogP:
2.67
PSA:
75.42
HBD:
1.0
HBA:
#RotB:
0.0
Source:
RX-518
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
RX-518
×
Maximum Phase:
1
First Approval:
None
UNII:
708TLB8J3Y
Molecule Type:
Small molecule
Molecular Formula:
C29H28F2N6O2
Molecular Weight:
530.58
AlogP:
4.56
PSA:
93.62
HBD:
3.0
HBA:
#RotB:
8.0
Source:
CH5132799
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
CH5132799
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MUBRITINIB
1
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms; Kidney Neoplasms; Lung Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms
Receptor protein-tyrosine kinase erbB-2 inhibitor
MUBRITINIB
×
Maximum Phase:
1
First Approval:
None
UNII:
V734AZP9BR
Molecule Type:
Small molecule
Molecular Formula:
C25H23F3N4O2
Molecular Weight:
468.48
AlogP:
6.06
PSA:
65.97
HBD:
0.0
HBA:
#RotB:
10.0
Source:
FLUOROACETATE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
FLUOROACETATE
×
Maximum Phase:
1
First Approval:
None
UNII:
AP1JV9U41M
Molecule Type:
Small molecule
Molecular Formula:
C2H3FO2
Molecular Weight:
78.04
AlogP:
0.04
PSA:
37.3
HBD:
1.0
HBA:
#RotB:
1.0
Source:
SC-43
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
SC-43
×
Maximum Phase:
1
First Approval:
None
UNII:
OT4AQX5MLU
Molecule Type:
Small molecule
Molecular Formula:
C21H13ClF3N3O2
Molecular Weight:
431.8
AlogP:
6.67
PSA:
74.15
HBD:
2.0
HBA:
#RotB:
4.0
Source:
ORDOPIDINE
1
Small molecule
Investigational
Unknown
Unknown
Parkinson Disease
Dopamine D2 receptor modulator
ORDOPIDINE
×
Maximum Phase:
1
First Approval:
None
UNII:
0P43SIA7J6
Molecule Type:
Small molecule
Molecular Formula:
C14H20FNO2S
Molecular Weight:
285.38
AlogP:
2.43
PSA:
37.38
HBD:
0.0
HBA:
#RotB:
3.0
Source:
YTTRIUM Y-90
1
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Hepatocellular
Unknown
YTTRIUM Y-90
×
Maximum Phase:
1
First Approval:
None
UNII:
1K8M7UR6O1
Molecule Type:
Small molecule
Molecular Formula:
Y
Molecular Weight:
89.91
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
SECLIDEMSTAT
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Sarcoma, Ewing
Unknown
SECLIDEMSTAT
×
Maximum Phase:
1
First Approval:
None
UNII:
TYH386V3WJ
Molecule Type:
Small molecule
Molecular Formula:
C20H23ClN4O4S
Molecular Weight:
450.95
AlogP:
2.14
PSA:
102.31
HBD:
2.0
HBA:
#RotB:
5.0
Source:
CORT 108297
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Glucocorticoid receptor antagonist
CORT 108297
×
Maximum Phase:
1
First Approval:
None
UNII:
A17W0640NB
Molecule Type:
Small molecule
Molecular Formula:
C26H25F4N3O3S
Molecular Weight:
535.56
AlogP:
5.09
PSA:
64.43
HBD:
0.0
HBA:
#RotB:
6.0
Source:
LY-3009120
1
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Melanoma; Neoplasm Metastasis
Serine/threonine-protein kinase A-Raf inhibitor
LY-3009120
×
Maximum Phase:
1
First Approval:
None
UNII:
1GDT36RARO
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
VT-1598
1
Small molecule
Investigational
Unknown
Unknown
Coccidioidomycosis
Unknown
VT-1598
×
Maximum Phase:
1
First Approval:
None
UNII:
AV9K9X720D
Molecule Type:
Small molecule
Molecular Formula:
C31H20F4N6O2
Molecular Weight:
584.53
AlogP:
4.88
PSA:
109.74
HBD:
1.0
HBA:
#RotB:
8.0
Source:
CICLOPIROX OLAMINE
1
Small molecule
Investigational
Unknown
Unknown
Dermatitis, Seborrheic; Tinea Pedis
Unknown
CICLOPIROX OLAMINE
×
Maximum Phase:
1
First Approval:
None
UNII:
50MD4SB4AP
Molecule Type:
Small molecule
Molecular Formula:
C14H24N2O3
Molecular Weight:
268.36
AlogP:
2.44
PSA:
42.23
HBD:
1.0
HBA:
#RotB:
1.0
Source:
1
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Molecular Formula
Molecular Weight
ALogP
PSA