Trade Names: | |
Synonyms: | |
Status: | Approved (1968) |
Entry Type: | Small molecule |
Molecule Category: | Salt |
UNII: | M6Q1EO9TD0 |
Parent Compound: | AMANTADINE |
InChI Key | WOLHOYHSEKDWQH-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C10H18ClN |
Molecular Weight | 187.71 |
AlogP | 1.91 |
Hydrogen Bond Acceptor | 1.0 |
Hydrogen Bond Donor | 1.0 |
Number of Rotational Bond | 0.0 |
Polar Surface Area | 26.02 |
Molecular species | BASE |
Aromatic Rings | 0.0 |
Heavy Atoms | 11.0 |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Ion channel
Ligand-gated ion channel
Ionotropic glutamate receptor
NMDA receptor
|
- | 75000 | - | - | - | |
Ion channel
Other ion channel
Miscellaneous ion channel
Type A influenza virus matrix-2 channel family
|
- | - | - | - | 0-35 | |
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 61 |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Influenza, Human | 4 | D007251 | FDA |
Severe Acute Respiratory Syndrome | 3 | D045169 | ClinicalTrials |
Multiple Sclerosis | 3 | D009103 | ClinicalTrials |
Brain Injuries | 2 | D001930 | ClinicalTrials |
Hepatitis C | 2 | D006526 | ClinicalTrials |
Psychotic Disorders | 1 | D011618 | ClinicalTrials |
Mood Disorders | 1 | D019964 | ClinicalTrials |
Schizophrenia | 1 | D012559 | ClinicalTrials |
Resources | Reference |
---|---|
ChEBI | 2619 |
ChEMBL | CHEMBL1569 |
EPA CompTox | DTXSID50874031 |
FDA SRS | M6Q1EO9TD0 |
Guide to Pharmacology | 4128 |
KEGG | C07939 |
PDB | 308 |
PubChem | 64150 |
SureChEMBL | SCHEMBL40713 |
ZINC | ZINC00968256 |