Synonyms: | |
Status: | Approved (1968) |
Entry Type: | Small molecule |
Molecule Category: | Parent |
ATC: | N04BB01 |
UNII: | BF4C9Z1J53 |
InChI Key | DKNWSYNQZKUICI-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C10H17N |
Molecular Weight | 151.25 |
AlogP | 1.91 |
Hydrogen Bond Acceptor | 1.0 |
Hydrogen Bond Donor | 1.0 |
Number of Rotational Bond | 0.0 |
Polar Surface Area | 26.02 |
Molecular species | BASE |
Aromatic Rings | 0.0 |
Heavy Atoms | 11.0 |
Primary Target | |
---|---|
GluN2C |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Ion channel
Ligand-gated ion channel
Ionotropic glutamate receptor
NMDA receptor
|
- | 92000-92000 | - | 10000 | - | |
Ion channel
Other ion channel
Miscellaneous ion channel
Type A influenza virus matrix-2 channel family
|
660-660 | 4700-16100 | 2170-12000 | - | 11-91 | |
Membrane receptor
|
- | - | - | 20 | - | |
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 10 | |
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC47 family of multidrug and toxin extrusion transporters
|
- | 37800 | - | - | 5 |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Parkinson Disease | 4 | D010300 | ClinicalTrials |
Schizophrenia | 3 | D012559 | ClinicalTrials |
Severe Acute Respiratory Syndrome | 3 | D045169 | ClinicalTrials |
Multiple Sclerosis | 3 | D009103 | ClinicalTrials |
Hepatitis C, Chronic | 3 | D019698 | ClinicalTrials |
Psychotic Disorders | 3 | D011618 | ClinicalTrials |
Hepatitis C | 2 | D006526 | ClinicalTrials |
Attention Deficit Disorder with Hyperactivity | 2 | D001289 | ClinicalTrials |
Cocaine-Related Disorders | 2 | D019970 | ClinicalTrials |
Cerebral Infarction | 2 | D002544 | ClinicalTrials |
Infections | 2 | D007239 | ClinicalTrials |
Pain | 2 | D010146 | ClinicalTrials |
Influenza, Human | 2 | D007251 | ClinicalTrials |
Diabetes Mellitus, Type 2 | 2 | D003924 | ClinicalTrials |
Mood Disorders | 1 | D019964 | ClinicalTrials |
Brain Injuries | 0 | D001930 | ClinicalTrials |
Resources | Reference |
---|---|
CAS NUMBER | 768-94-5 |
ChEBI | 2618 |
ChEMBL | CHEMBL660 |
DrugBank | DB00915 |
DrugCentral | 144 |
EPA CompTox | DTXSID8022117 |
FDA SRS | BF4C9Z1J53 |
Human Metabolome Database | HMDB0015051 |
Guide to Pharmacology | 4128 |
KEGG | C06818 |
PharmGKB | PA448360 |
PubChem | 2130 |
SureChEMBL | SCHEMBL4098 |
ZINC | ZINC000000968256 |